21 Of The Longest Words In English And What They Mean

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Would you believe that there are 21 of the longest words in English language that have more than 20 letters? As it turns out, these long words can be quite useful for showing off your vocabulary skills. But what do they mean? In this blog post, we’ll take a closer look at 21 of the longest words in English and what they mean. So whether you’re looking to impress your friends or just learn something new, keep reading!

21 of the Longest Words in English

Here are the 21 of the Longest Words in English:

1. Pneumonoultramicroscopicsilicovolcanoconiosis

Pneumonoultramicroscopicsilicovolcanoconiosis is one of the longest words in English, and it’s also one of the most difficult to pronounce. But what does it actually mean? The word was first used in 1935 by a doctor named E.M. Hoda, who defined it as “a chronic lung disease caused by the inhalation of very fine silica dust.” However, the word is now considered to be obsolete, and it’s rarely used in medical contexts.

Nevertheless, it remains a fascinating example of the flexibility of language. With a little creativity, it’s possible to create words that are both long and meaningful. And in an era of text messaging and Twitter, brevity is often overrated. So the next time you need to express a complex idea, don’t be afraid to reach for the dictionary. With a little effort, you might just find the perfect word.

2. Hippopotomonstrosesquippedaliophobia

Hippopotomonstrosesquippedaliophobia is one of the longest words in English. But it’s not just the length that makes it impressive, it’s also the meaning. The word describes a fear of long words, which might seem like a silly thing to be afraid of. But for those who suffer from hippopotomonstrosesquippedaliophobia, the fear is very real.

The word itself is derived from the Greek ‘hippopotamos’, meaning ‘river horse’, and ‘monstrōsēs’, meaning ‘monstrous’. The ‘equippedalis’ part comes from the Latin ‘equus’, meaning ‘horse’, and ‘pedalis’, meaning ‘foot’. So the word literally means ‘fear of long words that are like monsters with horse feet’.

It’s not known exactly how many people suffer from hippopotomonstrosesquippedaliophobia, but it is thought to be relatively rare. For those who do have the condition, it can be extremely debilitating. Just hearing a long word can trigger anxiety and panic, and in severe cases, even lead to avoidance behavior. If you know someone who has hippopotomonstrosesquippedaliophobia, it’s important to be understanding and patient. With treatment and support, they can overcome their fear and live a normal life.

3. Pseudopseudohypoparathyroidism

If you’re looking for a challenge, try pronouncing pseudopseudohypoparathyroidism. At 30 letters, it’s one of the longest words in the English language. And it’s not just a jumble of random syllables – it actually has a meaning.

Pseudopseudohypoparathyroidism is a condition that causes people to have the symptoms of hypoparathyroidism, even though their parathyroid glands are functioning normally. So what’s the pseudo all about? It comes from the Greek word for false, because the symptoms are false alarms.

Despite its length, pseudopseudohypoparathyroidism is a relatively rare condition – but that doesn’t make it any less confusing for those who have it.


Supercalifragilisticexpialidocious is one of the longest words in English, and it’s a perfect example of why length isn’t everything when it comes to words. The word was coined by Mary Poppins author P.L. Travers and first appeared in the 1964 Disney film adaptation of her book.

It’s a made-up word intended to convey the idea of something “extraordinary and wonderful,” and it succeeds admirably on both counts. The word is so playful and fun to say that it immediately puts a smile on your face, which is more than can be said for a lot of longer words.

In addition, its length makes it perfect for use in all sorts of creative endeavors, from children’s songs to crossword puzzles. So even though it may not be the most useful word in the English language, there’s no denying that supercalifragilisticexpialidocious is one of the most memorable.


Hepaticocholangiogastrostomy is one of the longest words in the English language, clocking in at 28 letters. That’s quite a mouthful! And it’s not even the longest word in medical terminology – that honor goes to pneumonoultramicroscopicsilicovolcanoconiosis, at 45 letters. So what does hepaticocholangiogastrostomy mean?

It’s a surgical procedure that involves connecting the hepatic duct (the main bile duct) to the stomach. The procedure is typically performed when there is a blockage in the bile duct that prevents bile from flowing into the intestine. By connecting the hepatic duct directly to the stomach, bypasses the blockage and allows bile to flow into the intestine as normal.

Hepaticocholangiogastrostomy is just one example of the many long words that can be found in medical dictionaries. So next time you’re feeling stuck for something to say, why not impress your friends with your knowledge of this very long word!

6. Radioimmunoelectrophoresis

As one of the longest words in English, “radioimmunoelectrophoresis” is certainly an impressive-sounding piece of vocabulary. But what does it actually mean? Radioimmunoelectrophoresis is a technique used to separate charged particles according to their size and charge. It relies on the fact that charged particles will be deflected when placed in an electric field.

By varying the strength of the electric field, radioimmunoelectrophoresis can be used to separates a wide range of particles, from small ions to large proteins. This makes it a valuable tool for research in many different fields, ranging from biology to geology.

So next time you see the word “radioimmunoelectrophoresis,” don’t be intimidated – just think of it as a long way of saying “electric field separation.

7. Antidisestablishmentarianism

Antidisestablishmentarianism is one of the longest words in English, and it’s also one of the most interesting. The word is made up of three parts: “anti-,” “disestablishment,” and “-arianism.” The “anti-” part is fairly self-explanatory; it means against or opposed to. “Disestablishment” is a bit more complicated. In this context, it means the act of ending state support for a particular church or religion. “-arianism” is a suffix that refers to a belief or doctrine.

So, put all together, antidisestablishmentarianism is the belief that the state should not support any particular church or religion.

Interestingly, the word was actually coined in the 19th century in opposition to the Disestablishment Act of 1833, which ended state support for the Church of England.

So, in a way, the word itself is a testament to the power of established institutions. After all, if the people who opposed the Disestablishment Act hadn’t come up with such a long and memorable word, it’s unlikely that the act would have been overturned.

In any case, antidisestablishmentarianism is a fascinating example of how a single word can encapsulate a complex political belief.

8. Spectrophotofluorometrically

English is a weird language. It’s full of words that are hard to pronounce, and it often doesn’t follow any logical rules. One of the longest words in English is “spectrophotofluorometrically.” It’s made up of four parts: “spectro,” meaning “light”; “photo,” meaning “light”; “fluoro,” meaning “fluorescence”; and “metrical,” meaning “measurement.”

The word is used to describe a process of measuring the amount of light that is absorbed by a material when it is exposed to light. While the word may be difficult to say, it’s actually quite simple conceptually. So next time you’re feeling challenged by a long word, just remember that it might not be as complicated as it seems.


Floccinaucinihilipilification is one of the longest words in the English language, and it’s also one of the most fun to say. The word comes from the Latin root words “floccus,” “naucum,” “nihilum,” and “pilus,” which all have to do with wool or hair. “Floccus” means “woolen tuft;” “naucum” means “nape of the neck;” “nihilum” means “nothing;” and “pilus” means “hair.”

Put them all together, and you get a word that means “the estimation of something as worthless.” In other words, it’s the act of regarding something as unimportant or not worth considering.

The word first appeared in print in 1741, in a work called A Classical Dictionary of the Vulgar Tongue by Francis Grose.

Since then, it has been used sparingly but has popped up from time to time in works by some fairly famous authors. In 1826, Edward Gibbon used it in The Decline and Fall of the Roman Empire: “…the decline of Rome was hastened by savage infants who, born in slavery, could not be impressed by the floccinaucinihilipilification of liberty.”


The word psychoneuroendocrinological is one of the longest words in the English language, and it’s also one of the most interesting. It’s a combination of three different words: psycho, which refers to the mind; neuro, which refers to the nervous system; and endocrine, which refers to the glands that produce hormones.

Together, these three word parts form a word that refers to the study of how the mind, nervous system, and hormones interact.

Psychoneuroendocrinology is a relatively new field of study, and it’s still uncovering a lot of fascinating information about how our minds and bodies work together. For example, recent research has shown that stress can cause physical changes in our bodies, including changes in hormone levels.

This research is helping us to understand how stress affects our health and well-being, and it’s also providing insight into how we can better manage stress. As we continue to learn more about psychoneuroendocrinology, we’re sure to uncover even more fascinating information about the mind-body connection.

11. Incomprehensibilities

Incomprehensibilities. There’s a word for you. It’s one of the longest words in English, and it pretty much sums up the last year for me. I’ve been working on a project that, frankly, has been incomprehensible at times. The goal has been to come up with a way to help people who feel stuck in their lives to find a new way forward.

And, while I’m not done yet, I’m starting to see results. Incomprehensibilities, though? That’s still the word that comes to mind when I think about the challenges I’ve faced along the way. But, hey, if you’re going to take on a big challenge, you might as

12. Immunoelectrophoretically

If you’re looking for a challenge, try saying “immunoelectrophoretically” five times fast. This tongue-twister of a word is one of the longest in the English language, clocking in at 25 letters. Though it may be a mouthful, immunoelectrophoresis is a relatively simple concept.

It’s a type of electrophoresis, which is a technique used to separate molecules based on their electric charge. In this case, the molecules being separated are antibodies, which are proteins produced by the immune system in response to foreign substances.

Immunoelectrophoresis is used to diagnose autoimmune disorders and other conditions in which the body produces abnormal amounts of antibodies. So next time you’re feeling ambitious, give this word a shot – but be prepared for a bit of a workout for your jaw muscles.

13. Uncopyrightable

As a marketer, I’m always looking for words that are both attention-grabbing and accurate. So when I came across the word “uncopyrightable,” I knew I had found a winner.

This word, which is featured in the Merriam-Webster dictionary, describes something that can’t be copyrighted. And while that might not seem all that useful at first glance, it actually has a lot of implications for marketers.

For one thing, it means that you can use this word in your marketing without having to worry about violating someone’s copyright. That’s because there’s no such thing as a copyright on this word. It’s in the public domain, which means anyone can use it however they want.

But beyond that, the word “uncopyrightable” also has a strong message attached to it. When you use this word, you’re effectively saying that your product or service is so unique and valuable that it can’t be copied. That’s a powerful statement to make, and it’s one that is sure to grab people’s attention.

So if you’re looking for a way to stand out from the competition, consider using the word “uncopyrightable” in your marketing. It’s a great way to get people’s attention and make a strong statement about your business at the same time.

14. Uncharacteristically

Uncharacteristically is one of the longest words in English. It’s often used to describe someone who’s not acting like themselves. For example, if you normally see your friend at the gym every day, but today they’re uncharacteristically skipping their workout, that means something’s up.

Maybe they’re sick, or maybe something else is going on. Either way, it’s not usual for them. Another example might be if someone is uncharacteristically late to a meeting. That might mean they had a hard time getting there, or it could be a sign that they don’t really care about the meeting.

Whatever the case may be, uncharacteristically is a great word to describe when someone isn’t acting like their normal selves.

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15. Psycholinguistics

Psycholinguistics is the study of how we produce and understand language. It’s a fascinating field that looks at everything from the way infants learn to speak to the way adults use language in everyday life. Psycholinguists also investigate the role of language in thought and cognition, and the relationship between language and culture.

And because language is such a central part of our lives, psycholinguistics has implications for many different disciplines, from psychology and neuroscience to anthropology and sociology. So whether you’re interested in how we acquire language or how we use it, psycholinguistics is a field that definitely merits further exploration.

16. Pneumoencephalographically

Pneumoencephalographically is one of the longest words in English, but what does it actually mean? This medical term refers to an imaging technique that is used to study the brain. It involves injecting air into the space between the brain and the skull.

This procedure creates a clear image of the brain, which can be used to diagnostic problems or track the progression of diseases. While pneumoencephalography is no longer used as often as it once was, it remains an important tool in the diagnosis of neurological disorders.

17. Psychophysicotherapeutics

25 letters long, “psychophysicotherapeutics” is one of the longest words in the English language. And it’s not just a made-up word for Scrabble players; it’s a real, albeit rare, term. So what does it mean? “Psychophysicotherapeutics” is actually two words smashed together: “psychophysical,” meaning relating to or involving both the mental and physical aspects of someone or something, and “therapeutics,” meaning the treatment of disease.

Put them together and you have a word that refers to the treatment of mental and physical diseases. Interestingly, “psychophysicotherapeutics” isn’t just long; it’s also one of the most precise words in the English language. There’s no wasted verbiage here; every letter serves a purpose. So next time you’re looking for a term that perfectly describes the treatment of both mind and body, reach for “psychophysicotherapeutics.”

18. Thyroparathyroidectomized

At 25 letters long, “thyroparathyroidectomized” is one of the longest words in the English language. But what does it mean? “Thyroparathyroidectomized” is a medical term that refers to the removal of the thyroid gland and the parathyroid glands. This surgery is typically performed to treat hyperparathyroidism, a condition in which the parathyroid glands secrete too much hormone.

The surgery is also sometimes used to treat thyroid cancer. While “thyroparathyroidectomized” may be a mouthful, it’s a good reminder that the English language is always evolving. As our understanding of the human body grows, so too do our medical terms. So next time you come across a long word like “thyroparathyroidectomized,” don’t be discouraged. Just think of it as another example of the English language at its best.


At 23 letters long, “otorhinolaryngological” is one of the longest words in the English language. It’s a mouthful to say, and it’s also a mouthful to define: the word refers to the study of the ear, nose, and throat. This branch of medicine is important for diagnosing and treating conditions that affect these parts of the body, including hearing loss, allergies, and sinus infections. While “otorhinolaryngological” may be a difficult word to pronounce, it’s an important one to know. After all, it’s responsible for keeping our sense of hearing, smell, and taste sharp.

20. Dermatoglyphics

Dermatoglyphics is one of the longest words in English, and it refers to the study of fingerprints. The word itself is derived from two Greek words: derma, meaning “skin,” and glyph, meaning “carving.” The study of fingerprints has a long history, dating back to ancient times.

In China, for example, fingerprint patterns were used for identification purposes as early as the ninth century. Today, dermatoglyphics is still used for a variety of purposes, including law enforcement and forensic science. In addition, the study of fingerprints can also provide insights into individual personality traits and health conditions.

So next time you come across this long word, remember that it’s not just pronounced “der-muh-tuh-GLIF-iks.” It also has a fascinating history and a range of practical applications.

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21. Bronchopneumonitis

Bronchopneumonitis is one of the longest words in English, clocking in at 21 letters. But it’s more than just a mouthful-it’s also a serious lung condition that can be caused by airborne viruses or bacteria. In Bronchopneumonitis, the bronchi (the large airways leading to the lungs) become inflamed and fill with fluid.

This can lead to difficulty breathing, coughing, and chest pain. In severe cases, Bronchopneumonitis can be life-threatening. While there is no cure for Bronchopneumonitis, early diagnosis and treatment is essential for preventing serious complications. So if you start feeling short of breath, don’t hesitate to see your doctor-you might just save your life.


As you can see, there are a lot of long words in the English language that have interesting uses. While some of them are so long that they are rarely used, they can still have a significant impact when they are. If you ever need to use one of these words, make sure you use it properly and don’t overuse it. Otherwise, you may risk sounding like you’re trying too hard or using big words for no reason.


What are the longest words in English?

The longest word in English is “antidisestablishmentarianism,” which is made up of 28 letters. Other long words include: “floccinaucinihilipilification” (29 letters), “pneumonoultramicroscopicsilicovolcanoconiosis” (45 letters), and “supercalifragilisticexpialidocious” (34 letters).

What do these long words mean?

Antidisestablishmentarianism means opposition to the disestablishment of the Church of England. Floccinaucinihilipilification means the act or instance of estimating as worthless. Pneumonoultramicroscopicsilicovolcanoconiosis is a lung disease caused by breathing in very fine particles of silicon dioxide. Supercalifragilisticexpialidocious means extremely wonderful.

Why are there so many long words in English?

There are a few reasons. First, English has a lot of loanwords from other languages. These foreign words often retain their original spelling, even if that means they’re longer than their English equivalents. Second, English speakers love to coin new words by combining existing ones. This can create very long words, like “antidisestablishmentarianism.” Finally, some long words are just the result of regular old word formation processes. For example, the word “pneumonoultramicroscopicsilicovolcanoconiosis” is made up of various smaller words meaning “lung,” “ultra-microscopic,” and “volcano.” When these words are put together, they create a new word that’s much longer than any of its parts.

What are some other long words in English?

Here are a few more long words: “honorificabilitudinitatibus” (27 letters), “pseudopseudohypoparathyroidism” (30 letters), “thyroparathyroidectomized” (25 letters), and “antidiarrheal” (12 letters).

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